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FR054 (b)
CAS No. 10378-06-0
FR054 (b)( (6R)-FR054 )
Catalog No. M23246 CAS No. 10378-06-0
FR054 is an inhibitor of the Hexosamine Biosynthetic Pathway (HBP) enzyme PGM3, with a remarkable anti-breast cancer effect.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 38 | In Stock |
|
| 10MG | 59 | In Stock |
|
| 25MG | 87 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameFR054 (b)
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NoteResearch use only, not for human use.
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Brief DescriptionFR054 is an inhibitor of the Hexosamine Biosynthetic Pathway (HBP) enzyme PGM3, with a remarkable anti-breast cancer effect.
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DescriptionFR054 is an inhibitor of the Hexosamine Biosynthetic Pathway (HBP) enzyme PGM3, with a remarkable anti-breast cancer effect.
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In Vitro——
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In Vivo——
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Synonyms(6R)-FR054
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PathwayApoptosis
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TargetApoptosis
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RecptorApoptosis|PGM3
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Research Area——
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Indication——
Chemical Information
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CAS Number10378-06-0
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Formula Weight329.31
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Molecular FormulaC14H19NO8
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Purity>98% (HPLC)
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SolubilityDMSO:100 mg/mL (303.67 mM; Need ultrasonic)
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SMILESCC1=N[C@@]([C@@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H](COC(C)=O)O2)([H])[C@@]2([H])O1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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LYG-202
LYG-202 is a novel flavonoid with piperazine substitution and antitumor effects in vivo and in vitro.LYG-202 induced apoptosis in MCF-7, MDA-MB-231, and MDA-MB-435 cells, and increased intracellular ROS production.
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BiP inducer X
BiP inducer X is a selective inducer of immunoglobulin heavy chain binding protein (BiP)/GRP78 and an ER chaperone inducer. BiP inducer X prevents cell death in neurons and retinal cell lines.
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KT5823
KT5823 is a selective and potent cGMP-dependent protein kinase (PKG) inhibitor with inhibitory effects on PKA and PKC.KT5823 increases thyroid-stimulating hormone-induced (Na+/I- symporter) NIS expression and iodide ion uptake by modulating sodium iodide symporter protein expression and activity in thyroid cells. KT5823 induces apoptosis.
